Bacteriology and Infectious Diseases

Bacterial Oncogenesis

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The most important diseases of concern to the medical community are cancer which arises from microbial origin. Microbial infection was found to cause 25% of all human tumours in which viral infection by oncogenic viruses constitutes the most tumours that develop from microbial origin. On the other hand, the role of bacteria in Oncogenesis has been largely neglected  for this reason; the current review was established to discuss the role of bacteria in the cancer incidence with particular emphasis on the mechanisms of bacterial carcinogenesis, most studies solely attribute bacterial carcinogenesis to host inflammatory response without discussing the role of bacterial factors in carcinogenesis in which many bacteria can exploit their host in various phases during their infection cycle with subsequent cell defects that affect cellular integrity and normal cellular functions resulting in cancer.

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Associations: International Society of Antimicrobial Chemotherapy| Emirates Medical Association | UAE Rare Disease Society| Emirates Neurology Society